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Spike protein inhibits CFTR recovery from endosomal recycling Under normal conditions, CFTR on the plasma membrane is subject to constitutive endosomal recycling in which misfolded or otherwise damaged CFTR is diverted towards destruction in the lysosome 47,48,49 (see Supplemental Fig

More human trials are needed to understand the potential of NAC in this capacity and examine the synergistic effect of NAC alongside pharmaceutical treatment

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However, since this is a single study, more research is required in this field (5)

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